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Issue #12 The Newbie Dilemma:
To Test or Not to Test
By Sanjac
Introduction
You've studied and researched for months, and you want to do your
first cycle. On the boards, you've read countless posts about hair
loss, gyno, liver damage, and prostate cancer, all caused by steroid
use. But none of this is going to happen to you, because you've
got it figured out. All those horrible side effects are caused by
the heavy androgens like Anadrol, trenbolone (fina), dbol, and particularly
testosterone. So, you're going to use the "anabolic" steroids, which
are much milder and safer than the androgenic steroids. Or at least
that's what everybody says...isn't it? This article will attempt
to dispel the misinformation that exists in the bodybuilding community
regarding the side effects of testosterone relative to the "anabolic"
steroids. As always, the author does not condone the use of steroids
by persons not under the care and guidance of a qualified physician.
Testosterone
First, let's take a look at what is known in the medical community
as the "natural" steroid, testosterone. Does testosterone cause
the horrible side effects listed above, and if so, how does testosterone
cause these effects?
Well, as for
hair loss, testosterone can be a contributing factor for those men
who are predisposed to male pattern baldness. Testosterone's effect
on hair loss can be made worse by the conversion of test to Dihydrotestosterone.
DHT forms via the action of 5-alpha reductase on testosterone. The
DHT-induced hair loss can be alleviated by using an enzyme inhibitor,
such as Finasteride (Proscar or Propecia). There are also several
topical treatments that reduce the effects of androgens on hair
loss. So, while testosterone can contribute to hair loss problems,
the problems can be reduced.
For the second
problem listed in the Introduction, gynecomastia ("bitch tits"),
testosterone does not cause this problem directly. Instead, testosterone
can be converted (by the aromatase enzyme) into estrogen, which
can cause the problem. A high estrogen level also causes water retention
and mood shifts in males, and may be responsible for increased acne.
So, we want to use an aromatase inhibitor and completely eliminate
the conversion of testosterone to estrogen, right? Not so fast!
Estrogen has some beneficial effects. First, estrogen is responsible
for maintaining the levels of key minerals in the body, particularly
in the bones. Over time, a lack of estrogen can lead to osteoporosis.
Second, estrogen is mostly responsible for the high energy levels
that many feel when on cycle. Finally, estrogen has been hypothesized
to play a role in building muscle, although this role is not understood.
So, if aromatase inhibitors are to be used, they should be used
sparingly. For example, a quarter of a milligram (0.25 mg) of arimidex
every other day appears to be sufficient to eliminate the negative
effects of estrogen, while still allowing a normal level to be present.
Alternatively, estrogen blockers such as Nolvadex and Clomid can
be used to prevent negative side effects of estrogen.
Many believe
that testosterone is harsh on the liver, because elevated liver
enzymes (ALT and AST) are observed with testosterone use. However,
these enzymes are not an accurate indicator of liver damage (resistance
training by itself causes elevated levels of these enzymes). Testosterone
(esters or suspension) has not been shown to increase GGT levels,
which would be a true indication of liver damage. So, testosterone
is well tolerated, even in elderly individuals (J. Clin. Endocrinal.
Metab., 83:10, 3435-3436).
Testosterone
also has not been shown to cause an elevated risk for prostate cancer,
although DHT (from testosterone) has been anecdotally linked to
Benign Prostatic Hyperplasia (it is important to note that there
is no statistical correlation between endogenous T and BPH, meaning
that there may not be an effect at all). As discussed under hair-loss,
DHT formation can be effectively prevented by the use of Proscar,
if the individual is susceptible to BPH.
Remember that
testosterone has been in the human body since the beginning of the
species. It is not "harsh", and the side effects are minor (and
can be controlled) in relation to the desired (muscle building)
effects of the molecule.
Synthetic
Steroids
What about the other steroids? Aren't they milder than testosterone?
Well, if you think about it, many of the synthetics appear to be
milder in their side effects, but they are also milder in the desired
effects, in comparison to testosterone. This means that you have
to use more to get similar results. Let's look at a few.
Nandrolone
(Deca) is probably the first choice for those who do not want to
use testosterone. Deca binds with greater affinity to the Androgen
Receptor than testosterone, and it has minimal impact on hair loss,
gyno, and BPH. However, deca does not effectively promote the non-AR
mediated paths to mass building, and it actually blocks some (neurotransmitter?)
paths that testosterone mediates, and the result is a loss of libido
and the inability to attain an erection ("deca-dick"). By itself,
it will stop endogenous testosterone production, and since it does
not aromatize, estrogen levels in the body will fall below normal
(not good). While deca is an excellent accessory steroid, it should
always be used in conjunction with testosterone to prevent these
effects.
Primobolan
is a highly regarded steroid, but because of its structure (ring
methylated at the A ring), it does not bind the AR as effectively.
Therefore, effective doses would be prohibitively expensive, and
by itself it would not be that useful. Primo will not aromatize
easily, and the lack of estrogen production without the presence
of testosterone is not desirable. Mesterolone and masteron
(drostanolone) are similar in effects.
Equipoise
is another accessory steroid, one that doesn't bind the AR as effectively
as testosterone. In conjunction with testosterone, it can help vascularity
and hardness, but by itself it is not that effective. It is believed
to be aromatizable, but the extent of estrogen formation is unknown.
Again, endogenous testosterone (and estrogen) levels will be affected.
Trenbolone
is a very effective steroid for mass building, but many believe
it to be too harsh and toxic for a beginner to even consider.
Oral Steroids
That leaves the 17-alpha alkylated steroids, the orals. Many beginners
don't want to use needles, so they think that taking an oral steroid
will be the best way to go. Nothing could be further from the truth.
All of the 17-alpha alkylated steroids can cause hepatic peliosis,
in which the liver forms internal pools of blood. The 17-alpha alkylated
steroids also have been implicated in the formation of liver tumors
(Nieschlag E, Behre HM, eds. 1998 Testosterone: Action, Deficiency,
Substitution, 2nd ed. Heidelberg/New York: Springer). The use of
an oral steroid by itself for mass building is ineffective because
of the high doses required to achieve the desired goals, and many
gains experienced with the orals are lost after cycle because the
gains were mostly water.
Dianabol
Dbol is very effective for helping to "jump-start" a cycle when
used in conjunction with testosterone. By itself, however, the mass
that would be added would consist of a lot of water (water is good
for strength increases), and the crash after the cycle would be
pretty bad. In addition, using Dbol for longer than 4-6 weeks can
increase the likelihood of liver (and kidney) problems.
Anadrol
A-50's are considered to be harsh and not suitable for beginners.
This is likely due to the high dosage of the 50 mg tablets. Even
at lower doses, the gains from Anadrol are mostly water.
Fluoxymesterone
(Halo)
While Halo doesn't appear to cause water gains, it also doesn't
do much for muscle gains. This steroid is not highly valued for
mass gains, although many value the perceived increases in aggression
when Halo is used.
Winstrol
(oral or injected)
While winny is valued in a stack with testosterone for its effect
on strength and muscle hardness, the doses that would be needed
if used alone would just exxagerate the toxic effects of this steroid.
Oxandrolone
This steroid is quite weak, and the expense of using it
by itself would be prohibitive. While it is quite mild in side effects,
the effects on muscle building are also quite mild.
CONCLUSION
While many of the steroids mentioned above are of benefit in a stack
with testosterone, they are ineffective when used alone. Even stacking
two or more of the synthetics will not yield the same results as
testosterone, and may cause greater side effects than testosterone.
A sound strategy for designing an effective cycle for beginners
and veterans alike is to use testosterone as the base steroid, and
add accessory steroids to achieve more of the desired effects.
Please address
any questions or comments to sanjac@operamail.com.
Copyright 2000, SJPreston
Copyright
2000 Jason Meuller and Anabolic Extreme. This material may not be
copied, reproduced, or transmitted without the express written permission
of the copyright owners.
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