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October 20, 2000
Issue #17

Protein Supplementation:  Something New???
by Dr. Seth Elliot

In the world of fitness and bodybuilding, we’ve seemingly heard it all when it comes to protein.  It all started out with recommendations to eat voluminous amounts of eggs, milk and beef to obtain enough protein, amino acids and of course nitrogen to “feed” and stimulate muscle growth.  Growing up, I always remember my dad speaking about his weight lifting days.  He was an officer in the United States Air Force in the early 60’s.  After a grueling day giving commands on a runway in Valdosta, Georgia, Craig Elliot would hit the gym with a few of his buddies.  I’ve seen a few of his pictures and I can tell you that he was quite muscular and fit.  Of course he was not large by today’s standards but at 5’11’’ and 200 he was not small either.  Now, according to my dad, the “thing to do” back then was to go to the local diner after you worked out, and fill up on a few eggs, a glass of milk, and maybe a steak if you were exceptionally hungry.  If you will notice, these are all high quality protein sources which seemed to work quite well.  This was the 60’s…in the 70’s things changed!

Sooner or later it was bound to happen!  Life was getting faster and faster in the 70’s.   People, including bodybuilders, were looking for ways to make their lives easier.  In our capitalistic environment, there was only one possible outcome and that was the creation of the protein shake.  For many years, there were just two possible choices—egg albumin (the white part of the egg) and casein (a milk protein).  Both of these are high quality proteins but back then they were not instantized and so they required a blender to prevent the creation of a shake that looked like something from the peat boggs in Scotland.  Let me explain briefly the concept of instantization.  A protein is designed to be highly soluble in aqueous mediums.  This characteristic is essential but it means that if you were to take regular ole protein powder and throw it in a glass of milk, it would immediately clump and lump up on you.  Because the protein powder is so incredibly soluble, the part of the powder which immediately contacts the aqueous fluid dissolves and turns into a functional film which surrounds the rest of the powder…thus forming the lumps and clumps.  Today, we rarely see such a phenomenon because all of the protein powders have been physically modified to disperse and go uniformly into solution.  There are two main ways this is accomplished and the best protein powders use both.  The first and most important is what is known as agglomeration.  Agglomeration makes the particles of the protein powder irregular and of different sizes.  Practically, this allows the aqueous fluid to penetrate the powder (and any lumps) much more efficiently.  The other technique is to lecithinate the powder.  The only thing this means is that the particles of the protein powder are coated with lecithin which is a natural, healthy emulsification and dispersion agent.  The lecithin works by temporarily changing the characteristics of the aqueous medium surrounding the particle.  This prevents the protein from gelling and sticking together and forming clumps.  Together, agglomerating and lecithinating do a fantastic job in making a protein powder convenient and easy to use.

Casein and egg albumin reigned supreme until the 90’s when a little-known protein by the name of whey was introduced to the fitness world.  Almost overnight, this protein displaced the sales of casein and egg and became one of the most popular dietary supplements of all time.  Why and how did this happen?  Well, there are two reasons.  One, whey was the first protein powder that was really marketed by capitalizing on the fact that it was instantized.  Before this, few protein powders were instantized and most people just couldn’t handle the trouble of using a blender several times per day to adequately blend the protein powder.  Whey was hyped as the ultimate protein powder that EVEN would instantly blend with a spoon into your milk or water.  Second, whey was hyped and lied about to the extremes calling it the absolute highest quality protein known to man.  Reading the advertisements, you would think that a person using it would become Frank Zane overnight.  Now, I’ll admit that whey is high quality but in reality it is no better than total egg protein.  In fact, total egg protein has a Biological Value (BV) of 100 and whey a BV of 94.  Shamefully, supplement companies, and the magazines that owned them, were printing that whey protein had a BV above 160.  They were also using big words like hydrolyzed, and di-, tri-, and oligo-peptides.  All of this deception basically fooled the average Joe into thinking that he couldn’t live without whey protein—that it was the very key to his muscular growth. 

Once the whey protein mystique was perpetuated, there was little hope for any other protein source.  I remember that my friend a few years ago would not feel satisfied eating eggs as his protein source.  Once in awhile he would come over to my house to eat breakfast and we would have eggs.  He would have probably four or five and then rush home to get his whey protein shake.  I told him that this was ridiculous but he would hear nothing of it.  You see, his magazines told him that whey was better so in his mind it was and so he wasn’t able to live without it.  The sad thing is that the protein in the eggs was overall a better and more utilizable protein source than his whey shake.

Whey wasn’t the only protein that was refined and marketed in the 90’s.  The technology behind soy protein isolates improved dramatically thus making them high quality, instantized, and palatable.  A few products were introduced with soy protein isolate throughout the 90’s but they never seemed to take off.  Like casein and egg albumin, soy too was stricken by the success of whey and was living in its shadow so to speak.  This was unfortunate because soy isolate is not only economical but is a very good protein at promoting lean muscle gains and keeping the fat stores down to a minimum. 

All of this talk of protein foods and supplements is all good and dandy but practically speaking where are we right now; what are we to do?  Well, I can tell you one thing and that is that the supplement companies could care less about telling you the truth about which protein supplement is best.  They are only interested in promoting their bottom line and this doesn’t necessarily mean giving the customer the truth.  I am going to present some very new insights into protein supplementation that are backed by documented scientific evidence that will have you looking at and supplementing dietary proteins in an entirely new light.  In the past, we have seen nothing but the promotion of single sources of dietary proteins.  Once in awhile you might find an egg and casein blend but for the most part you could only buy a container of just egg albumin powder or casein powder or whey powder.  The reason for this is that various supplement companies would stake their claim by saying that one protein source was vastly superior to another one.  Once they made such a claim, they were locked in and could not then mix their “superior” protein with an “inferior” one.  The latest result of this phenomenon was the vast hype and promotion of whey protein.  Nearly every supplement company jumped on the whey bandwagon and excluded every protein source from their supplements except for whey.  Because all the supplement companies (and the magazines that are owned by them) committed to this particular course of action, it prevented any truly truthful information from being disseminated to the consumer.  Thus, for the last ten years, athletes from all walks of life have been kept in the dark regarding how to properly supplement their diet with protein.   

The first notion that I want to dispel is that the usefulness of a protein supplement for an athlete is directly related to one of the protein quality rating scales that are currently in use.  Many exist but the most common ones that are used by the fitness community are Biological Value (BV) and Protein Digestibility Corrected Amino Acid Score (PDCAAS).  Basically, BV and PDCAAS rate how perfect the ratio of amino acids are for “WHOLE BODY GROWTH AND MAINTENANCE”.  On a daily basis, your body requires specific amounts of amino acids for the growth and maintenance of proteinaceous bodily tissues and processes.  If a high percentage of the amino acids in an ingested protein are directly used by these tissues and processes, then the protein will be efficiently used and the BV and PDCAAS will consequently be extremely high.  If, however, the protein source has a bunch of amino acids in high amounts that the body doesn’t need then these will not be used efficiently and the resulting score will be rather low.  Now, this is where it gets interesting people!  BV and PDCAAS measure the efficiency of a protein for WHOLE BODY growth and maintenance.  Remember that there are tons of proteinaceous tissues in the body besides muscle tissue.  With PDCAAS and BV you have no idea if certain proteinaceous tissues are consuming the bulk of these amino acids preferentially over other tissues.  As an example, a certain protein might have a high BV but it might do very little to add growth to muscle tissue.  It is quite possible that much of the protein is preferentially used in other tissues and process such as connective tissue repair, etc.  Believe it or not, there is ongoing research right now to elucidate this phenomenon.  I wish I could disclose the particulars right now but I am prevented from doing so because of confidentiality agreements.  I will say though that in the near future you will be seeing several new protein sources that have been shown to stimulate muscle tissue growth better than high quality protein sources such as casein and spray dried porcine plasma. 

Am I saying that these new protein sources will take over the protein supplement industry?  Of course not!  I wouldn’t even recommend this to happen.  We would be in the same position that we are in now.  Although these particular proteins might do well at stimulating muscle growth, they might not do well at supplementing other important bodily processes and the overall health of the individual might suffer.  I am, and always have been, a firm believer in combining various protein sources.  Would you be satisfied with just consuming maltodextrin or sucrose as your only carbohydrate?  Would you be satisfied consuming only olive oil as your only fat source?  Of course not!  Our bodies were not designed to eat just one type of a particular macronutrient like protein or carbohydrate.  Like fats and carbohydrates, different proteins have different effects on the human body.  Finally, in the last several months we are seeing a little bit of this come into play with the various whey/casein combinations.  These are an improvement but they still are not good enough.  One thing you must be aware of with these protein supplements is that certain companies will try to use the inferior caseinate instead of micellar casein.  How can you tell the difference?  Well, you could call the company but good luck getting any honest information.  Or, you could look at the label and see how much sodium, potassium, and calcium is listed.  If there are significantly greater amounts listed than what is on the label of a whey protein supplement, then the company is trying to sell you inferior goods.  To reap the wonderful benefits of casein, you must use undenatured, micellar casein!  Although the casein/whey combination is better than any stand-alone protein, it is still not good enough.  What we are after is a combination of 3-5 proteins that will give the user a wide variety of benefits for optimal health and muscle growth.   

If I had my way, I would use whey protein for its very high BV and for its immune system stimulating properties.  Whey protein is also good to use because it is absorbed into the bloodstream very quickly which is essential when using a protein supplement after a workout.  I would then add micellar casein since it also has a high BV and has been shown to be significantly anticatabolic to muscle tissue.  Casein is also a good choice because it balances the quick-acting properties of whey.  The micellar nature of casein causes it to be released very slowly into the blood and gives the user a very ideal, steady flow of amino acids to the target tissues.  Now, this is probably the absolute best you will see on the market right now but there is so much more to be had from a protein supplement.  To the above whey/casein, I would add some soy protein isolate as it has been shown to significantly reduce fat deposits in comparison to milk proteins.  Furthermore, soy protein isolate has been shown to lower cholesterol and actually improve thyroid function as well as kidney function.  You might think I am done, but I have saved the best for last.  I would add good portions of the two proteins that I previously mentioned which specifically stimulate muscle growth.  These proteins have a fairly good BV and cause much greater muscle growth than even casein!  Even better, one of these proteins even causes VERY reduced fat deposits in comparison to casein.  This combination gives you the best of all worlds:  a protein that gives everything you need for whole body growth and maintenance, as well as slow and fast absorption rates, as well as improved thyroid and kidney function, as well as lower cholesterol levels, as well as DIRECTLY stimulated muscle growth and DIRECTLY stimulated fat catabolism.  What more could you ask for!

Unfortunately, no supplement company is even thinking about a protein supplement like this right now.  Soon, the research lab that I am working with will complete their preliminary trials and will look for companies of integrity to market such a product.  It may be a few months but keep your eyes on the lookout for the next generation of protein  supplementation.  Until then, try to buy several different types of proteins and mix them together to achieve as many beneficial characteristics as possible.  They say that variety is the spice of life.  When it comes to protein supplements, I couldn’t agree more that variety is the key to perfection!

Dr. Seth Elliot is one of the leading minds in developing efficacious dietary supplements that are based on sound science.  One of his special areas of expertise is in the area of various proteins and their effects on the human body.  If you have any questions, please go to our CONTACT US section and send him an email. 

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